Choroidal Metastasis of Non-Small Cell Lung Cancer That Responded to Gefitinib

نویسندگان

  • Iwao Shimomura
  • Yuji Tada
  • Gen Miura
  • Toshio Suzuki
  • Takuma Matsumura
  • Kenji Tsushima
  • Jiro Terada
  • Ryota Kurimoto
  • Emiko Sakaida
  • Ikuo Sekine
  • Yuichi Takiguchi
  • Shuichi Yamamoto
  • Koichiro Tatsumi
چکیده

A 52-year-old Japanese woman presented with optical symptoms, including left-sided myodesopsia, blurred vision, narrowed visual field, and diminished visual acuity. Ocular evaluation revealed a metastatic tumor in the choroid. Further examinations identified pulmonary adenocarcinoma as the primary tumor. Because an epidermal growth factor receptor gene (EGFR) mutation was detected in a biopsy specimen, gefitinib treatment was initiated. Dramatic responses were obtained in the primary tumor and metastatic foci. Optical symptoms improved and remained stable for 5 months during the treatment, until relapse. This report demonstrates that gefitinib is effective for choroidal metastasis of pulmonary adenocarcinoma harboring an EGFR mutation.

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عنوان ژورنال:

دوره 2013  شماره 

صفحات  -

تاریخ انتشار 2013